Progressive Retinal Atrophy (PRA) refers to a group of inherited blinding canine diseases. Depending on the mutation the blindness develops faster or slower. A large number of varieties of PRA are currently known to affect several breeds. (Scientific) research is continuously developing new tests.
Test specific information
This test is patented in certain countries. We offer our clients two options for this test because we are not allowed to perform the test in our laboratory.
Firstly, the test can be ordered through a licensee of the patent owner.
As a second option, the test can be forwarded to a partner laboratory in non-patented territory.
Between these two options, a price difference is in place which is caused by the royalties costs on the test. The tests performed by both labs are technical identical.
The disease may show itself on different ages, in which it cannot be estimated when the first symptoms may show themselves. Differences may exist between littermates, and between breeds.
The Turnaround Time (TAT) depends on various factors, such as the shipment time of your sample to the test location, the test method(s) and whether the tests are performed completely or partially by a Partner Lab or Patent owner.
The TAT of tests performed at our facilities is normally 10 working days after receipt of the sample at the testing laboratory (VHL, VHP or Certagen). For tests performed by a Partner Laboratory (so-called "partner lab test") or patent owner, the TAT is at least 20 working days after receipt of your sample. Because the shipment time to our Partner Labs or patent owner may vary due to factors we cannot influence, the mentioned 20 working days are therefore an estimate.
Sometimes it is necessary to re-run your sample. We call this a retest. In that case, the TAT will of course be extended.
Location of disease or trait
This disease mainly affects vision, and may result in blindness.
This DNA test is available for the following breeds: American Cocker Spaniel, American Eskimo Dog, Australian Cattle Dog, Australian Labradoodle, Australian Shepherd, Australian Shepherd Miniature & Toy, Australian Silky Terriër, Australian Stumpy Tail Cattle Dog, Black Russian Terrier, Bolognese, Chesapeake Bay Retriever, Chinese Crested, Cockapoo, Coton de Tulear, Dwarf Poodle, English Cocker Spaniel, English Springer Spaniel, Entlebucher Mountain Dogs, Field Spaniel, Finnish Lapphund, Giant Schnauzer, Giant Spitz, Golden Retriever, Goldendoodle, Hungarian Puli, Jack Russell Terrier, Japanese Chin, Karelian Beardog, Kuvasz, Lab/Golden Cross, Labradoodle, Labrador Retriever, Lagotto Romagnolo (Romagna Water Dog), Lancashire Heeler, Lapponian Herder, Manchester Terrier, Markiesje, Medium Spitz, Miniature American Sheperd, Miniature and Toy Poodle, Miniature Spitz, Moyen Poodle, Norrbottenspitz, Norwegian Elkhound, Nova Scotia Duck Tolling Retriever, Pomeranian, Portuguese Podengo Pequeno, Portuguese Water Dog, Russian-European Laika, Schipperke, Serbian Hound, Spanish Water Dog, Swedish Lapphund, Tibetian Terrier, Wolfspitz, Xoloitzcuintli, Yorkshire Terrier. Additional information is available in the Frequently Asked Questions (FAQ).
For this DNA test we accept the following materials: Blood EDTA, Blood Heparin, Semen, Swab, Tissue. Please contact Dr. Van Haeringen Laboratorium if you wish to submit other material as listed.
An animal can be free and has in that situation two healthy alleles. When used in breeding this animal will not become ill due to the disease. It cannot spread the disease in the population.
An animal can be carrier and has in that situation one healthy and one disease allele. When used in breeding 50 percent of the offspring will receive the disease allele. Carriers will not become ill.
An animal can be affected and has in that situation two disease alleles. When used in breeding all offspring will also receive the disease allele. Affected will become ill.
This genetic factor is inherited in an autosomal, recessive, mode. This means, that the individual can be free of the disease (homozygote normal), affected (homozygous affected) or carrier (heterozygous).
Carriers may spread the mutation in a population without showing symptoms themselves. Because of this, it is extremely important to identify carriers correctly to prevent spreading of a mutation.
Severity of Disease