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In dogs with Alexander disease (GFAP) astrocytes, which are supportive cells of the central nervous system are malfunctioning.
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Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Year Published |
General information
In dogs with Alexander disease (GFAP) astrocytes, which are supportive cells of the central nervous system are malfunctioning. This causes neurodegenerative disorders.
Clinical features
Dogs with Alexander disease display symptoms within a few hours to a maximum of several weeks after birth. The puppies are weak or almost paralyzed. They can show spastic front limbs which is known as “swimming puppy syndrome”.
Additional information
References
Pubmed ID: 26486469
Omia ID: 1208
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