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H338

Acute respiratory distress syndrome (ARDS) is described as an exaggerated inflammantory response within the longs.

10 working days

Specifications

Breeds

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Also known as

Year Published

General information

Acute respiratory distress syndrome (ARDS) is described as an exaggerated inflammantory response within the longs. The ANLN gene encodes for an anillin actin binding protein, which is suggested to regulate the integrity of intercellular junctions. A defective ANLN could result in abnormal cellular organization of the bronchiolar epithelium, which subsequently leads to acute respiratory distress.

Clinical features

Clinical features include progressive tachypea and dyspnea could lead to a severe respiratory distress and euthanasia. In addition, puppies could undergo renal aplasia and hydrocephalus.

Additional information

References

Pubmed ID: 28222102

Omia ID: 101

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