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Acute respiratory distress syndrome (ARDS) is described as an exaggerated inflammantory response within the longs.
10 working days
Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
General information
Acute respiratory distress syndrome (ARDS) is described as an exaggerated inflammantory response within the longs. The ANLN gene encodes for an anillin actin binding protein, which is suggested to regulate the integrity of intercellular junctions. A defective ANLN could result in abnormal cellular organization of the bronchiolar epithelium, which subsequently leads to acute respiratory distress.
Clinical features
Clinical features include progressive tachypea and dyspnea could lead to a severe respiratory distress and euthanasia. In addition, puppies could undergo renal aplasia and hydrocephalus.
Additional information
References
Pubmed ID: 28222102
Omia ID: 101
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