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In general, impaired hearing with age is normal in dogs with an onset at 8-10 years.
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Specifications
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specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
General Information
In general, impaired hearing with age is normal in dogs with an onset at 8-10 years. Early (E) Adult onset deafnessis (AOD) a hearing disease in Border Collies has an early onset at 3-5 years. EAOD is considered to be problematic, in especially working Border Collies, because hearing slight differences in tones is essential to the function of a working Border Collie. Even moderate hearing loss can already have a major impact on working ability.
The gradual hearing loss is observed at the age of 3-5 years affecting both ears.
This test include the results of 4 associated markers for Adult Onset Deafness (EAOD).
Additional information
This test is based on a genome wide association study in which multiple DNA variants in close proximity to the usp31 gene on chromosome 6 were discovered that are related to Early Adult Onset Deafness (EAOD) in Border Collies. Each DNA variant is a “risk factor” and VHLGenetics tests for those that have been published with the "highest risk".
Clinical features
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