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In general, impaired hearing with age is normal in dogs with an onset at 8-10 years.

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Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Also known as

Year Published

General information

In general, impaired hearing with age is normal in dogs with an onset at 8-10 years. Early Adult Onset Deafness (EAOD) is a hearing disease in Border Collies and has an early onset at 3-5 years. EAOD is considered to be problematic, in especially working Border Collies, because hearing slight differences in tones is essential to the function of a working Border Collie. Even moderate hearing loss can already have a major impact on working ability.

Clinical features

The gradual hearing loss is observed at the age of 3-5 years affecting both ears.

Additional information

This test is based on an association study in which multiple DNA variants in close proximity to the usp31 gene on chromosome 6 were discovered that are related to Early Adult Onset Deafness (EAOD) in Border Collies. Each DNA variant is a “risk factor”. VHLGenetics tests only for those variants that have been published with the "highest risk".

The test could have potential benefits for breeders whose dogs have deafness somewhere in their pedigree, for assist in making a breeding choice. It is described in the literature that the presence of deafness in the pedigree greatly increases the chances that these risk variants are associated with the causal mutation for EAOD, which has not been discovered yet.

In case of a CARRIER/AFFECTED result for the 4 variants, this test indicates that the dog has an increased risk on whether or not to develop EAOD. It is not known how great this increased risk is, it could be entirely possible that your at risk dog is not carrying the causal mutation at all. If your dog's test results come back as CARRIER/AFFECTED, this information could be used to make sure the dog you breed him/her to is CLEAR for the respective variants.


Pubmed ID: 23028339

Omia ID: 2550

How does it work?

1. Select your product(s)

Select your single test, a CombiBreed Package or create your own Bundle.

2. Collect DNA sample

Collect DNA material as indicated with our products and send it to our laboratory.

3. Results

We handle your DNA sample with care and provide you with the results.

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