Hair Length Dog (5 variants)

Hair length in dogs is a trait largely controlled by the gene “fibroblast growth factor 5” (FGF5). Several different recessive mutations to this gene can result in the growth of longer hair, such as the breed-typical coat of the Afghan Hound, or the Fluffy variant of the French Bulldog. The variants analysed in this test are as follows:

L1: c.284G>T p.(C95F)
L2: c.578C>T p.(A193V)
L3: c.556_571del p.(A186Tfs*71)
L4: c.559_560dup p(R188Afs*75)
L5: c.368-11T>A

Dogs carrying any combination of two of these mutations (being Affected by one mutation, or being a Carrier for two) are expected to have long hair. Dogs that are only Carriers for a single mutation are expected to have short hair.

Note that the specific length of a dog’s coat can also be influenced by other genes in the breed’s genetics.