Muscular Dystrophy (MD) – Cavalier King Charles Spaniel
...to the DMD gene. The variant analysed in this test is found in the Cavalier King Charles Spaniel, and is sometimes known as Cavalier King Charles Spaniel Muscular Dystrophy (CKCS-MD)....
MCAD Deficiency – Cavalier King Charles Spaniel
...(MCADD). This results in a build-up of medium-chain fatty acids, causing neurological symptoms such as fatigue and seizures. In dogs, MCAD Deficiency is found in the Cavalier King Charles Spaniel....
Macrothrombocytopenia (MTC) – Cavalier King Charles Spaniel
...apparently healthy animal. The variant in this test occurs in the Cavalier King Charles Spaniel and is caused by a recessive mutation in TUBB1. This form is generally considered mild:...
CombiBreed Cavalier King Charles Spaniel
...Heterozygosity percentage is a measure of your dog’s individual genetic diversity. Information about individual tests in this package is available in the section ‘Included Tests’ on this page. We accept...
Degenerative Myelopathy Exon 2 (SOD1A)
...Border Collie Borzoi Boxer Boykin Spaniel Cardigan Welsh Corgi Cavalier King Charles Spaniel Chesapeake Bay Retriever Czechoslovakian Wolfdog English Springer Spaniel French Bulldog German Shepherd Dog Glen of Imaal Terrier...
Copper toxicosis in Labrador Retrievers
...informed decisions to avoid producing puppies with two copies of the ATP7B mutation, which would greatly reduce the likelihood of severe copper accumulation. This is achieved by avoiding the mating...
Neuronal Ceroid Lipofuscinosis 10 (NCL10) – American Bulldog
...ultimately death. The variant analysed in this test, Neuronal Ceroid Lipofuscinosis 10 (NCL10), is caused by a recessive mutation to the gene CTSD. It is found in the Amerian Bulldog....
Xanthinuria, type 2 – Spaniel variant
...by a recessive mutation to the gene MOCOS. The variant of the disorder analysed in this test is found in the Cavalier King Charles Spaniel and English Cocker Spaniel. Related...
Myxomatous Valvular Degeneration (MMVD, 3 variants)
...the atrium (regurgitation). This leads to heart failure over time. The disease occurs more often in males and breeds like Cavalier King Charles Spaniels and Dachshunds. Three mutations are tested...
Episodic Falling Disease – EFS (External Lab)
Episodic Falling Syndrome (EFS), also called Episodic Hypertonicity, Hyperekplexia or Paroxysmal Exercise-Induced Dystonia, is a neurological disorder found in the Cavalier King Charles Spaniel. The disease causes episodes of muscle...
Episodic Falling Disease – EFS (External Patent Lab)
Episodic Falling Syndrome (EFS), also called Episodic Hypertonicity, Hyperekplexia or Paroxysmal Exercise-Induced Dystonia, is a neurological disorder found in the Cavalier King Charles Spaniel. The disease causes episodes of muscle...
Dry Eye Curly Coat Syndrome (CCS, DE-CC)
Congenital Keratoconjunctivitis Sicca and Ichthyosiform Dermatosis (CKCSID), colloquially known as ‘Dry Eye Curly Coat Syndrome’, is a disorder found in the Cavalier King Charles Spaniel. There are two elements to...
Primary Immunodeficiency Type 2 (PIPS2, CARMIL2-related) – CKCS
...unable to produce a protein critical for proper immune function, making them highly susceptible to respiratory infections. This variant of the disorder is specifically found in Cavalier King Charles Spaniels....
Recessive Lethal (FH4 & FH10) – Friesian
Reduced fertility can have various causes, including both genetic and environmental factors. Recently, two genetic variants associated with early embryonic recessive lethality have been identified in the Friesian horse breed:...