Cerebellar Degeneration-Myositis Complex (CDMC) – NSDTR
Cerebellar Degeneration-Myositis Complex (CDMC) is a severe, degenerative neuromuscular disorder that causes muscle weakness, atrophy and ultimately death. It is caused by a recessive mutation to the gene SLC25A12. The...
Cortical Cerebellar Abiothrophy (NCCD) – Vizsla
Cerebellar cortical degeneration (CCD) is a neurodegenerative disease process affecting many dog breeds. The disease affects a specific area of the brain known as the cerebellum. In cerebellar degeneration, the...
Neuronal Ceroid Lipofuscinosis 6 (NCL6) – Australian Shepherd
Neuronal Ceroid Lipofuscinosis (NCL) is the name referring to a wide array of degenerative neurological conditions which cause progressive nerve damage, resulting in a loss of mobility and vision, and...
Neuronal Ceroid Lipofuscinosis 8-2 (NCL8-2)
Neuronal Ceroid Lipofuscinosis (NCL) is a wide array of degenerative neurological conditions which cause progressive nerve damage, resulting in a loss of mobility and vision, and ultimately death. This variant,...
Gangliosidosis (GM2 Type I) – Japanese Chin
Gangliosidosis (GM2 Type I) is a fatal, progressive neurodegenerative disease caused by mutations in the HEXA and HEXB genes. These mutations lead to a deficiency of an enzyme that is...
Neuronal Ceroid Lipofuscinosis 5 (NCL5) – Golden Retriever
Neuronal Ceroid Lipofuscinosis (NCL) is the name referring to a wide array of degenerative neurological conditions which cause progressive nerve damage, resulting in a loss of mobility and vision, and...
Neuronal Ceroid Lipofuscinosis 12 (NCL12) – Australian Cattle Dog
Neuronal Ceroid Lipofuscinosis (NCL) is the name referring to a wide array of degenerative neurological conditions which cause progressive nerve damage, resulting in a loss of mobility and vision, and...
Achromatopsia 2 (Day Blindness) – Labrador Retriever
Achromatopsia (ACHM), also called Cone Degeneration Disease (CD), is a degenerative disorder of the retinas that damages cone cells and causes vision loss, colour blindness and sensitivity to light. This...
Gangliosidosis (GM1) – Cat All Breeds
Gangliosidosis (GM1) is a fatal neurodegenerative disease. The lysosomal enzyme β-D-galactosidase cleaves terminal galactose residues from a variety of molecules. Due to a mutation the enzyme cannot be produced properly...
Neuronal Ceroid Lipofuscinosis 7 (NCL7)
Neuronal Ceroid Lipofuscinosis (NCL) is the name referring to a wide array of degenerative neurological conditions which cause progressive nerve damage, resulting in a loss of mobility and vision, and...
Neuronal Ceroid Lipofuscinosis 10 (NCL10) – American Bulldog
Neuronal Ceroid Lipofuscinosis (NCL) is the name for a wide array of degenerative neurological conditions which cause progressive nerve damage, resulting in a loss of mobility and vision, and ultimately...
Neuronal Ceroid Lipofuscinosis 8 (NCL8) – Saluki
Neuronal Ceroid Lipofuscinosis (NCL) is the name referring to a wide array of degenerative neurological conditions which cause progressive nerve damage, resulting in a loss of mobility and vision, and...
Neuronal Ceroid Lipofuscinosis 12 (NCL12) – Tibetan Terrier
Neuronal Ceroid Lipofuscinosis (NCL) is the name for a wide array of degenerative neurological conditions which cause progressive nerve damage, resulting in a loss of mobility and vision, and ultimately...