Neuronal Ceroid Lipofuscinosis 1 (NCL1) – Cane Corso
Neuronal Ceroid Lipofuscinosis (NCL) is the name referring to a wide array of degenerative neurological conditions which cause progressive nerve damage, resulting in a loss of mobility and vision, and...
Neuronal Ceroid Lipofuscinosis 5 (NCL5)
Neuronal Ceroid Lipofuscinosis (NCL) is the name for a wide array of degenerative neurological conditions which cause progressive nerve damage, resulting in a loss of mobility and vision, and ultimately...
Cerebellar Abiotrophy (CA) – Kelpie
Cerebellar Abiotrophy is a hereditary neurodegenerative disorder affecting the cerebellum. The cerebellum is the part of the brain responsible for balance, coordination, and fine motor control. In Kelpies this condition...
Neuronal Ceroid Lipofuscinosis 6 (NCL6) – Schapendoes
Neuronal Ceroid Lipofuscinosis 6 (NCL6) is a hereditary neurodegenerative lysosomal storage disorder caused by mutations in the ceroid‑lipofuscinosis neuronal 6 (CLN6) gene. This defect leads to the build‑up of lipopigments,...
Neuronal Ceroid Lipofuscinosis 8 (NCL8) – Alpine Dachsbracke
Neuronal Ceroid Lipofuscinosis 8 (NCL8) is a hereditary neurodegenerative lysosomal storage disorder caused by mutations in the Ceroid‑Lipofuscinosis Neuronal 8 (CLN8) gene. This defect leads to the build‑up of lipopigments,...
Neuronal Ceroid Lipofuscinosis 4A (NCL4A) – Cerebellar Ataxia
Neuronal Ceroid Lipofuscinosis (NCL) is a wide array of degenerative neurological conditions which cause progressive nerve damage, resulting in a loss of mobility and vision, and ultimately death. This specific...
Gangliosidosis (GM2 Type II) – Cat All Breeds
Gangliosidosis (GM2 Type II) is a fatal, progressive neurodegenerative disease caused by mutations in the HEXA and HEXB genes. These mutations lead to a deficiency of an enzyme that is...
Cerebellar Degeneration-Myositis Complex (CDMC) – NSDTR
Cerebellar Degeneration-Myositis Complex (CDMC) is a severe, degenerative neuromuscular disorder that causes muscle weakness, atrophy and ultimately death. It is caused by a recessive mutation to the gene SLC25A12. The...
Cortical Cerebellar Abiothrophy (NCCD) – Vizsla
Cerebellar cortical degeneration (CCD) is a neurodegenerative disease process affecting many dog breeds. The disease affects a specific area of the brain known as the cerebellum. In cerebellar degeneration, the...
Neuronal Ceroid Lipofuscinosis 6 (NCL6) – Australian Shepherd
Neuronal Ceroid Lipofuscinosis (NCL) is the name referring to a wide array of degenerative neurological conditions which cause progressive nerve damage, resulting in a loss of mobility and vision, and...
Neuronal Ceroid Lipofuscinosis 8 (NCL8) – Australian Shepherd Type
Neuronal Ceroid Lipofuscinosis (NCL) is a wide array of degenerative neurological conditions which cause progressive nerve damage, resulting in a loss of mobility and vision, and ultimately death. This variant,...
Gangliosidosis (GM2 Type I) – Japanese Chin
Gangliosidosis (GM2 Type I) is a fatal, progressive neurodegenerative disease caused by mutations in the HEXA and HEXB genes. These mutations lead to a deficiency of an enzyme that is...
Neuronal Ceroid Lipofuscinosis 5 (NCL5) – Golden Retriever
Neuronal Ceroid Lipofuscinosis (NCL) is the name referring to a wide array of degenerative neurological conditions which cause progressive nerve damage, resulting in a loss of mobility and vision, and...
Neuronal Ceroid Lipofuscinosis 12 (NCL12) – Australian Cattle Dog
Neuronal Ceroid Lipofuscinosis (NCL) is the name referring to a wide array of degenerative neurological conditions which cause progressive nerve damage, resulting in a loss of mobility and vision, and...
Achromatopsia 2 (Day Blindness) – Labrador Retriever
Achromatopsia (ACHM), also called Cone Degeneration Disease (CD), is a degenerative disorder of the retinas that damages cone cells and causes vision loss, colour blindness and sensitivity to light. This...