Muscular Dystrophy (MD) – Cavalier King Charles Spaniel
Muscular Dystrophy (MD) is an X-linked muscular disorder, equivalent to Duchenne Muscular Dystrophy (DMD) in humans. The disorder is severe and ultimately fatal, and causes progressive degradation of the dog’s...
Muscular Dystrophy (MD) – Corgi
Muscular Dystrophy (MD) is an X-linked muscular disorder, equivalent to Duchenne Muscular Dystrophy (DMD) in humans. The disorder is severe and ultimately fatal, and causes progressive degradation of the dog’s...
MCAD Deficiency – Cavalier King Charles Spaniel
Medium-chain acyl-CoA dehydrogenase (MCAD) is an enzyme that helps the body process medium-chain fatty acids, forming a key part of an animal’s metabolism. A recessive mutation to the gene ACADM...
Muscular Dystrophy (MD) – French Bulldog
Muscular Dystrophy (MD) is a hereditary neuromuscular disorder caused by mutations in the Duchenne Muscular Dystrophy (DMD) gene. This gene encodes dystrophin, a protein essential for maintaining the structural stability...
Leukodystrophy (CYTB-related)
Canine Spongiform Leukoencephalomyelopathy (SLEM), also known as simply Leukodystrophy, is a severe degenerative neurological disease that causes weakness, paralysis and spastic movement. The disorder is caused by a mitochondrial mutation...
New test for Leukodystrophy in the Australian cattle dog and Shetland sheepdog
Canine Spongiform Leukoencephalomyelopathy, also known as simply Leukodystrophy or SLEM, is a severe degenerative neurological disease that causes weakness, spastic movement and paralysis. In the Australian Cattle Dog and the...
Australian Labradoodle Dystrophinopathy
Australian Labradoodles can be affected by a disease called Australian Labradoodle Dystrophinopathy. This disorder is a variant of Duchenne Muscular Dystrophy (DMD) and causes damage to the skeletal muscles and...
Gangliosidosis (GM2 Type II) – Poodle Type
Gangliosidosis (GM2 Type II) is a fatal, progressive neurodegenerative disease caused by mutations in the HEXA and HEXB genes. These mutations lead to a deficiency of an enzyme that is...
Hereditary Ataxia (SCA) – Australian Shepherd
Progressive Degenerative Myeloencephalopathy is a form of hereditary ataxia, sometimes referred to as spinocerebellar ataxia (SCA). This severe neurological disorder leads to a loss of coordination, muscle weakness, and sensory...
Neuronal Ceroid Lipofuscinosis 1 (NCL1) – Dachshund
Neuronal Ceroid Lipofuscinosis (NCL) is a wide array of degenerative neurological conditions which cause progressive nerve damage, resulting in a loss of mobility and vision, and ultimately death. The variant...
Neuronal Ceroid Lipofuscinosis 2 (NCL2) – Dachshund
Neuronal Ceroid Lipofuscinosis (NCL) is the name for a wide array of degenerative neurological conditions which cause progressive nerve damage, resulting in a loss of mobility and vision, and ultimately...
Lagotto Storage Disease (LSD)
...as Lysosomal Storage Disease (LSD), aberrant autophagy or Neurodegenerative Vacuolar Storage Disease. An autosomal recessive mutation in the ATG4D gene causes this LSD, which is observed in the Lagotto Romagnolo....
Neuronal Ceroid Lipofuscinosis 8 (NCL8) – English Setter
Neuronal Ceroid Lipofuscinosis (NCL) is a wide array of degenerative neurological conditions which cause progressive nerve damage, resulting in a loss of mobility and vision, and ultimately death. This variant,...
Alaskan Husky Encephalopathy (AHE)
Alaskan Husky Encephalopathy (AHE) is a severe neurodegenerative disease unique to Alaskan Huskies. AHE causes neurological deficits such as seizures and loss of coordination, and is ultimately fatal. The disorder...
Warburg Micro Syndrome 1 (WARBM1)
Warburg Micro Syndrome, type 1 (WARBM1) is a form of polyneuropathy, a severe degenerative nerve condition that causes vision problems, an altered voice, and lack of coordination. The onset starts...