57,48 47,50 excl. VAT

H490

Gangliosidosis type 1 (GM2, B variant), also known as Sandhoff disease, is an early onset form of lysosomal storage disease.

10 working days

Specifications

Breeds

,

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Also known as

Year Published

General information

Gangliosidosis type 1 (GM2, B variant), also known as Sandhoff disease, is an early onset form of lysosomal storage disease. It causes a buildup of ganglioside (a type of glycolipid) in cells of various tissue but especially in the nervous system.

Clinical features

Dogs affected with Gangliosidosis type 1 (GM2, B variant) show neurologic signs as puppies or young adults. These include vision loss, behavior changes, abnormal gait, and seizures.

Additional information

References

Pubmed ID: 22766310

Omia ID: 1462

How does it work?

1. Select your product(s)

Select your single test, a CombiBreed Package or create your own Bundle.

2. Collect DNA sample

Collect DNA material as indicated with our products and send it to our laboratory.

3. Results

We handle your DNA sample with care and provide you with the results.

Related products