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H312

A development disorder causing craniomandibular osteopathy (CMO).

10 working days

Specifications

Breeds

, ,

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Year Published

General information

A development disorder causing craniomandibular osteopathy (CMO). CMO is a self-limiting proliferative bone disease seen in young dogs. It manifests between 4 to 8 months of age.

Clinical features

Swelling of the jaw, periodical fever, lack of appetite, pain, difficulty opening the mouth and dysphagia. Bony lesions caused by excessive proliferation. Especially found on the mandible and tympanic bulla, but occasionally also on the metaphyses of long bones.

CMO is a clinical equivalent to an infantile cortical hyperostosis in humans (Caffey disease).

Additional information

References

Pubmed ID: 27187611

Omia ID: 2244

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