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H308

Canine degenerative myelopathy (DM) is an incurable progressive neurodegenerative disease of the spinal cord.

10 working days

Specifications

Breeds

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Also known as

Year Published

General information

Canine degenerative myelopathy (DM) is an incurable progressive neurodegenerative disease of the spinal cord. Neurodegenerative diseases are characterised by progressive loss of neurons in the central nervous system (CNS) which leads to deficiencies in brain function of the affected region. DM is similar in many ways to Amyotrophic Lateral Sclerosis (ALS) in humans.

Clinical features

Most dogs are at least 8 years of age at the onset of the first clinical signs which include hyporeflexia, spasticity and ataxia of the pelvic with progression over time to complete paralysis.

Additional information

References

Pubmed ID: 21628865

Omia ID: 263

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2. Collect DNA sample

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3. Results

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