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Cats have several different possible serotypes (blood types): Type A, Type B and the more uncommon Type AB (sometimes known as Type C).
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Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Year Published |
General information
Cats have several different possible serotypes (blood types): Type A, Type B and the more uncommon Type AB (sometimes known as Type C). Type A is “normal”; Types B and AB can be caused by a number of recessive mutations to the gene CMAH.
Besides being relevant for medical issues such as blood transfusion, a cat’s serotype is significant for breeding. If a kitten with Serotype A is born to a mother with Serotype B, it is at risk from the A-targeting antibodies in the mother’s milk. This causes a potentially lethal reaction known as Feline Isoerythrolysis Neonatalis (IN) or “Fading Kitten Syndrome”.
This test analyses for the rare mutation a^c, which causes blood type AB. The a^c allele is recessive to N (Type A), but dominant to b (Type B).
Clinical features
The A/B blood group system is clinically important in cats because mismatched breeding and transfusions can cause life threatening hemolytic reactions without prior sensitization. Therefore, a complete genetic characterization of all feline blood types is crucial so that genetic testing can accurately report an individual’s blood type.
Additional information
Due to the many possible mutations that can cause blood type B, it is not always possible to identify a cat's blood type through genetics alone.
The serological test (K712) directly determines your cat’s serotype: A (N/N), B (b/b) or AB (N/b). This can only be tested on a blood sample.
References
Pubmed ID: 27171395
Omia ID: 119