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Cats have several different possible serotypes (blood types): Type A, Type B and the more uncommon Type AB (sometimes known as Type C).
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Specifications
| Breeds | |
|---|---|
| Gene | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Year Published |
General information
Cats have several different possible serotypes (blood types): Type A, Type B and the more uncommon Type AB (sometimes known as Type C). Type A is “normal”; Types B and AB can be caused by a number of recessive mutations to the gene CMAH.
Besides being relevant for medical issues such as blood transfusion, a cat’s serotype is significant for breeding. If a kitten with Serotype A is born to a mother with Serotype B, it is at risk from the A-targeting antibodies in the mother’s milk. This causes a potentially lethal reaction known as Feline Isoerythrolysis Neonatalis (IN) or “Fading Kitten Syndrome”.
This test analyses for two associated mutations (designated ‘b’) that cause Type B blood.
Clinical features
Additional information
The genetic test for determining blood group in cats is available for most domestic breeds, but accuracy for wild cats is unknown due to a lack of reference samples. In a small percentage of all cases, results may be inconclusive due to unidentified genetic variations. This occurs more often in the Maine Coon breed. The test can determine if a cat likely has Serotype AB, but if negative, it cannot differentiate between Serotype A or B. Serological testing (K712) is necessary to precisely determine if the cat has Serotype A, B, or AB, and this requires a blood sample. It is important to note that while blood typing tests can provide valuable information, they may not prevent all instances of newborn deaths.
References
Pubmed ID:
Omia ID: 119