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Sensory neuropathy is a severe neurological disease caused by recessive mutation in the FAM134B gene.
10 working days
Swab, Blood EDTA, Blood Heparin, Semen, Tissue
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Sensory neuropathy is a severe neurological disease caused by recessive mutation in the FAM134B gene. The disease causes the degeneration of sensory and nerve cells, and often results in self-mutilation of the paws.
Affected puppies manifest at approximately 7 months of age with ataxia (loss of coordination) in the limbs. The disease progresses to cause loss of sensation, "knuckling" of the hind paws and self-mutilation of the paws, which often necessitates surgical amputation of damaged toes.
Pubmed ID: 34387380
Omia ID: 2032