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H777

Hereditary Footpad Hyperkeratosis (HFH) is a skin disorder of the footpads, which causes the development of thick, painful, callus-like growths.

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Specifications

Breeds

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Also known as

Year Published

General information

Hereditary Footpad Hyperkeratosis (HFH) is a skin disorder of the footpads, which causes the development of thick, painful, callus-like growths. This variant of the disorder, found in the Rottweiler, is caused by a recessive mutation to the gene DSG1. The disorder is also known as Palmoplantar Hyperkeratosis.

Clinical features

Symptoms for HFH affected dogs start at about 8 weeks of age, with footpads appearing unusually dry. The pads develop thick, rapidly-growing horny growths, which are painful and can cause additional discomfort while standing. The condition may also leave the dog more susceptible to additional skin and ear infections.

Additional information

References

Pubmed ID: 32344723

Omia ID: 2266

How does it work?

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2. Collect DNA sample

Collect DNA material as indicated with our products and send it to our laboratory.

3. Results

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