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Cat blood types are defined by the presence of N-glycolylneuraminic acid (NeuGc) (type A) and N-acetylneuraminic acid (NeuAc) (type B) and the rare blood type AB with the presence of both.
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General information
Cat blood types are defined by the presence of N-glycolylneuraminic acid (NeuGc) (type A) and N-acetylneuraminic acid (NeuAc) (type B) and the rare blood type AB with the presence of both. In Ragdoll cats, recently a CMAH mutation was identified which is highly associated with blood type AB. Presence of both NeuGc and NeuAc can be explained by a reduced CMAH activity (aAB/ aAB or aAB/b).
Clinical features
The A/B blood group system is clinically important in cats because mismatched breeding and transfusions can cause life threatening hemolytic reactions without prior sensitization. Therefore, a complete genetic characterization of all feline blood types is crucial so that genetic testing can accurately report an individual’s blood type.
Additional information
The Blood Group AB genetic test for Ragdoll cats (K300) can determine whether your cat likely has Serotype AB (N/b) or not. If negative, it does not determine whether the cat has Serotype A (N/N) or B (b/b).
The serological test (K712) directly determines your cat’s serotype: A (N/N), B (b/b) or AB (N/b). This can only be tested on a blood sample.
References
Pubmed ID: 27171395
Omia ID: 119
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