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Cat blood types are defined by the presence of N-glycolylneuraminic acid (NeuGc) (type A) and N-acetylneuraminic acid (NeuAc) (type B) and the rare blood type AB with the presence of both.
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General information
Cat blood types are defined by the presence of N-glycolylneuraminic acid (NeuGc) (type A) and N-acetylneuraminic acid (NeuAc) (type B) and the rare blood type AB with the presence of both. In Ragdoll cats, recently a CMAH mutation was identified which is highly associated with blood type AB. Presence of both NeuGc and NeuAc can be explained by a reduced CMAH activity (aAB/ aAB or aAB/b).
Clinical features
The A/B blood group system is clinically important in cats because mismatched breeding and transfusions can cause life threatening hemolytic reactions without prior sensitization. Therefore, a complete genetic characterization of all feline blood types is crucial so that genetic testing can accurately report an individual’s blood type.
Additional information
References
Pubmed ID: 27171395
Omia ID: 119
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