€57,48 €47,50 excl. VAT
Hyperekplexia, also known as Startle Disease, is a neurological disorder.
10 working days
€5,95 shipping and administration per order (incl. VAT)
Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Year Published |
General information
Hyperekplexia, also known as Startle Disease, is a neurological disorder. As the name implies, its main symptom is an exaggerated startle response that can result in episodes of sudden stiffness and collapse. The specific variant of the disorder analysed in this test is found in the Miniature Australian Shepherd. It is caused by a recessive mutation to the gene GLRA1.
Clinical features
Within the first weeks of life, affected puppies are prone to collapsing when startled by certain noises or sights, or if otherwise excited. Collapse episodes tend to last about ten seconds, during which the dog remains conscious but displays stiff limbs (particularly the hind legs), as well as difficulty breathing. At their most severe, these episodes can be life-threatening, and euthanasia on humane grounds may be considered.
Additional information
References
Pubmed ID: 37222814
Omia ID: 689
Related products
-
- Bernese Mountain Dog
- SOD1
- Nervous system
-
- All Breeds
- MITF
- Integumentary system
-
- Dachshund, Parson Russell Terrier, Smooth Fox Terrier, Jack Russell Terrier
- KCNJ10
- Nervous system
-
- All Breeds
- None
