€57,48 €47,50 excl. VAT
Spinocerebellar Ataxia (SCA) is a disease of progressive incoordination of gait and loss of balance.
10 working days
Swab, Blood EDTA, Blood Heparin, Semen, Tissue
|Mode of Inheritance|
|Also known as|
Spinocerebellar Ataxia (SCA) is a disease of progressive incoordination of gait and loss of balance. This variant of the disorder, found in the Parson Russell Terrier, is caused by a recessive mutation to the gene CAPN1.
The chief symptom of SCA is uncoordinated gait (ataxia) with characteristic “dancing" or “prancing” leg movements. Clinical signs usually become notable between 6 and 12 months of age. Especially during the initial months of disease, the degree of truncal ataxia, pelvic limb hypermetria (overreaching with the hind legs) and impaired balance is progressive. During the later stages of the disease walking often becomes difficult. In the interest of animal welfare, owners of affected dogs often opt for euthanasia.
Pubmed ID: 23741357
Omia ID: 1820