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Spinocerebellar ataxia (SCA) is a disease of progressive incoordination of gait and loss of balance.

10 working days

Specifications

Breeds

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Also known as

Year Published

General information

Spinocerebellar ataxia (SCA) is a disease of progressive incoordination of gait and loss of balance. The cerebellum (part of the brain) fine-tunes motor signals from the brain to the muscles, allowing for balance and coordination.

Clinical features

An uncoordinated gait (ataxia) with characteristic “dancing" or “prancing” leg movements. Clinical signs usually become notable between 6 and 12 months of age. Especially during the initial months of disease, the degree of truncal ataxia, pelvic limb hypermetria and impaired balance is progressive. During the later stages of the disease walking often becomes difficult, making owners decide to euthanize affected dogs because of animal welfare reasons.

Additional information

References

Pubmed ID: 23741357

Omia ID: 1820

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