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Progressive rod–cone degeneration (PRCD) is one of the many disorders grouped with progressive retinal atrophy (PRA).
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Specifications
| Breeds | Chinese Crested, Poodle (Miniature), Poodle (Standard), Poodle (Toy), Australian Cattle Dog, Australian Shepherd, Australian stumpy tail cattle dog, Chesapeake Bay Retriever, Cocker Spaniel, English Cocker Spaniel, Entlebucher mountain dog, Finnish Lapphund, Golden Retriever, Karelian Bear Dog, Kuvasz, Labrador Retriever, Lapponian Herder, Norwegian Elkhound, Nova Scotia Duck Tolling Retriever, Portuguese Water Dog, Spanish Water Dog, Swedish Lapphund, Yorkshire Terrier |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
General information
Progressive rod–cone degeneration (PRCD) is one of the many disorders grouped with progressive retinal atrophy (PRA). Prcd is a late-onset, autosomal recessive photoreceptor degeneration caused by a mutation in the PRCD-gene.
Clinical features
Loss of night vision and progressive loss of day vision. During bilateral fundus examination it is common to find changes such as pigmentation, vascular changes, hyperreflexia, and optic nerve atrophy. These changes can already be found during an early stage of the disease.
Additional information
This test is based on an association study.
References
Pubmed ID: 16938425
Omia ID: 1298
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