Polycystic Kidney Disease (PKD) occurs frequently in animals. During the life of an affected aminal, cysts appear in the kidneys. These cysts put pressure on the healthy kidney-tissue, which leads to a loss of function of the affected kidneys.
Polycystic Kidney Disease causes progressive loss of kidney function. The symptoms become apparent at an adult age. Symptoms are loss of appetite, excessively drinking and urinating, vomiting, lethargy and neurologic behavior.
Only the Persian and Persian-derived cat breeds (Exotic Shorthairs and Himalayans) have been recognized to have a high frequency of PKD. Other breeds have either purposely or accidentally bred to Persians.