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Pituitary Dwarfism is a hormonal disorder that results in retarded growth and sometimes an abnormal coat.
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Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Year Published |
General information
Pituitary Dwarfism is a hormonal disorder that results in retarded growth and sometimes an abnormal coat. This particular variant of the disorder, found in the Karelian Bear Dog, is caused by a recessive mutation to the gene POU1F1.
Clinical features
Affected puppies present with reduced or retarded growth. They also display coat abnormalities; some affected dogs might never lose their puppy coat, while others may develop an adult coat before losing most of it.
Additional information
References
Pubmed ID: 33550451
Omia ID: 2315