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The protein lactate dehydrogenase isoform A, encoded by the gene LDHA, is critical to metabolism of different tissues and to overall physiological performance.
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General information
The protein lactate dehydrogenase isoform A, encoded by the gene LDHA, is critical to metabolism of different tissues and to overall physiological performance. The gene is therefore a useful performance marker for homing pigeons.
LDHA is an enzyme that is responsible for both the synthesis and recycling of lactate in the muscles. A pigeon that is homozygous for A (carries two copies of the isoform A allele) is a better race performance bird, though it is a rare variation in racing pigeons, meaning only a minority of pigeons have this allele.
Clinical features
Having the isoform A means that lactate can be recycled more efficiently and re-used in the muscles, leading to the capability to maintain a certain speed for a longer period of time.
Additional information
References
Pubmed ID: 16424611
Omia ID: