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Inherited Myopathy of Great Danes (IMGD) is a rapidly progressive muscle myopathy.
10 working days
Swab, Blood EDTA, Blood Heparin, Semen, Tissue
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Inherited Myopathy of Great Danes (IMGD) is a rapidly progressive muscle myopathy. IMGD results from a recessive mutation in the bridging integrator 1 (BIN1) gene. Affected dogs suffer from a progressive muscle atrophy and have a decreased ability to perform physical exercise. Only 20% of affected dogs survive to adulthood with acceptable quality of life according to previous research data.
IMGD presents at an age of onset around six months. Affected dogs are unable to perform physical exercise, display exercise-induced muscle tremors, and develop progressive muscle atrophy.
Pubmed ID: 23754947
Omia ID: 1660