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Haemophilia A, also called Factor VIII Deficiency, is the most common bleeding disorder in dogs.

15 working days






Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance


Also known as

Year Published

General information

Haemophilia A, also called Factor VIII Deficiency, is the most common bleeding disorder in dogs. Caused by an X-linked recessive mutation to the gene F8, the disease strongly impairs the blood’s ability to clot, which can lead to severe symptoms such as spontaneous internal bleeding, or uncontrolled bleeding after injury or surgery. This specific variant of the disease is one of two to occur in the German Shepherd. Related variants are also found in the Irish Setter and Miniature Schnauzer, Boxer, Old English Sheepdog, and the Rhodesian Ridgeback.

Clinical features

Common clinical signs in dogs included: bleeding from the mouth, subcutaneous and intramuscular haematomas and lameness.

Additional information

This test is patented in certain countries. We offer our clients two options for this test because we are not allowed to perform the test in our laboratory. Firstly, the test can be ordered through a licensee of the patent owner. As a second option, the test can be forwarded to a partner laboratory in non-patented territory.

This is an X-linked disease.

This test is performed by an external laboratory. CombiBreed takes care of the mediation between you as a customer and the external laboratory. In this case, CombiBreed cannot be held liable for the behaviour of the client and/or contractor.


Pubmed ID: 21949058

Omia ID: 437

How does it work?

1. Select your product(s)

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2. Collect DNA sample

Collect DNA material as indicated with our products and send it to our laboratory.

3. Results

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