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Thyroid follicular cell carcinomas (FCC) are mainly classified into four types: follicular thyroid carcinoma (FTC), papillary thyroid carcinoma (PTC), compact thyroid carcinoma (CTC), and follicular-compact thyroid carcinoma (FCTC).
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Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
General information
Thyroid follicular cell carcinomas (FCC) are mainly classified into four types: follicular thyroid carcinoma (FTC), papillary thyroid carcinoma (PTC), compact thyroid carcinoma (CTC), and follicular-compact thyroid carcinoma (FCTC). The upregulation of mitogen-activated protein kinase (MAPK) and phoshpatidylinositol-3-kinase (PI3K)/Akt signaling pathways was reported to cause the FCC in dogs and humans. The TPO gene was identified to be associated with FCC.
Clinical features
Clinical signs include the presence of cervical mass, intermittent cough, alopecia, polyuria, polydipsia, weight loss and lethargy.
Additional information
This test is based on a genome wide association study which described two highly associated markers. Therefore, these markers should be tested together.
References
Pubmed ID: 34209805, 34464021
Omia ID: 2380
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