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H497

Dystrophic epidermolysis bullosa is an inherited skin disorder which causes blistering in the skin and the mucosal membranes.

10 working days

Specifications

Breeds

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue
Mode of Inheritance

Chromosome

Also known as

Year Published

General information

Dystrophic epidermolysis bullosa is an inherited skin disorder which causes blistering in the skin and the mucosal membranes. The skin of affected dogs stretches and tears easily. Therefore affected dogs must be monitored closely and treated immediately for any injuries.

Clinical features

Multiple vesicles, bullae and ulcers in the oral and oropharyngeal mucosa, inner pinnae, dorsal plane of the nose, ventral abdomen, external genital and footpads. Symptoms are recognizable soon after birth. Histological examination shows separation at the dermal-epidermal junction with cleft formation.

Additional information

References

Pubmed ID: 12874109

Omia ID: 341

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