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Canine degenerative myelopathy (DM) is an incurable progressive neurodegenerative disease of the spinal cord.
15 working days
Specifications
| Breeds | Belgian Sheepdog, Poodle (Miniature), Poodle (Standard), Wire Fox Terrier, Alaskan Malamute, American Eskimo dog, Bernese Mountain dog, Boxer, Cardigan Welsh Corgi, Chesapeake Bay Retriever, German Shepherd Dog, Golden Retriever, Hovawart, Kerry Blue Terrier, Pembroke Welsh Corgi, Pug, Rhodesian Ridgeback, Siberian Husky, Soft Coated Wheaten Terrier |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
General information
Canine degenerative myelopathy (DM) is an incurable progressive neurodegenerative disease of the spinal cord. Neurodegenerative diseases are characterised by progressive loss of neurons in the central nervous system (CNS) which leads to deficiencies in brain function of the affected region. DM is similar in many ways to Amyotrophic Lateral Sclerosis (ALS) in humans.
Clinical features
Most dogs are at least 8 years of age at the onset of the first clinical signs which include hyporeflexia, spasticity and ataxia of the pelvic with progression over time to complete paralysis.
Additional information
This test is based on an association study. This test is performed by an external laboratory. CombiBreed takes care of the mediation between you as a customer and the external laboratory. In this case, CombiBreed cannot be held liable for the behaviour of the client and/or contractor.
References
Pubmed ID: 19188595
Omia ID: 263
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