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H681

A recessive mutation to the keratin gene KRT71 is responsible for the growth of a curly rather than straight coat in certain dogs.

10 working days

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Specifications

Breeds

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Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Year Published

General information

A recessive mutation to the keratin gene KRT71 is responsible for the growth of a curly rather than straight coat in certain dogs. The variant analysed in this test, designated as c^2, is found in breeds such as the Bichon Frise, Chesapeake Bay Retriever, Curly Coated Retriever and Lagotto Romagnolo. A closely related variant, designated as c^1, is found in the Portuguese Water Dog.

Clinical features

Affected dogs will have curly instead of straight hairs.

Additional information

There are some indications that the variant possibly represents a genetic risk factor for some forms of follicular dysplasia in dogs.

References

Pubmed ID: 30444027,30456859

Omia ID: 245

How does it work?

1. Select your product(s)

Select your single test, a CombiBreed Package or create your own Bundle.

2. Collect DNA sample

Collect DNA material as indicated with our products and send it to our laboratory.

3. Results

We handle your DNA sample with care and provide you with the results.