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A recessive mutation to the keratin gene KRT71 is responsible for the growth of a curly rather than straight coat in certain dogs.
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Specifications
| Breeds | Bichon Frise, Chesapeake Bay Retriever, Curly-coated retriever, Irish Terrier, Lagotto Romagnolo, Spanish Water Dog |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Year Published |
General information
A recessive mutation to the keratin gene KRT71 is responsible for the growth of a curly rather than straight coat in certain dogs. The variant analysed in this test, designated as c^2, is found in breeds such as the Bichon Frise, Chesapeake Bay Retriever, Curly Coated Retriever and Lagotto Romagnolo. A closely related variant, designated as c^1, is found in the Portuguese Water Dog.
Clinical features
Affected dogs will have curly instead of straight hairs.
Additional information
There are some indications that the variant possibly represents a genetic risk factor for some forms of follicular dysplasia in dogs.
References
Pubmed ID: 30444027,30456859
Omia ID: 245