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The Dominant White coat colour pattern in horses can be caused by any in a wide array of related mutations.
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Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Hair, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Year Published |
General information
The Dominant White coat colour pattern in horses can be caused by any in a wide array of related mutations. The resulting pattern can vary anywhere between white markings on the face and legs, up to a completely white coat. Depending on both breed and pattern, variants of the Dominant White phenotype may be referred to as Splashed White, White Spotting, Tobiano or Sabino, among others.
The variant analysed in this test, known as Tobiano, is caused by an incomplete dominant mutation to the gene KIT. The variant is present in approximately 86% of Lewitzer horses with tobiano patterning, and has also been found in the Irish Cob, Gypsy Vanner and Tinker.
Clinical features
The Tobiano white-spotting pattern is characterized by general and distinct oval or round patches of depigmented skin and coat. The depigmentation extend down over the neck and chest, which can be seen as a shield. The extent of the depigmentation can range from approximately 20% to 80% of the body surfaces. The spotting pattern is present at birth and stable throughout life.
Additional information
Coat colour is an intricate trait that involves a combination of multiple different genes. Testing for a range of different loci will give the most complete prediction of a horse's coat colour genetics.
Dominant White can be caused by a wide range of mutations. A white-patterned horse that tests as unaffected for a particular mutation will almost certainly be affected by a different one.
References
Pubmed ID: 18410476
Omia ID: 209