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The RALY gene (hnRNP associated with lethal yellow) defines whether tan points or saddle tan is expressed.
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Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Year Published |
General information
The RALY gene (hnRNP associated with lethal yellow) defines whether tan points or saddle tan is expressed. The coat colour is further complicated by the interaction with the E-locus, K-locus, A-locus and a yet unidentified gene.
Clinical features
Black and tan colour is characterised by light colour on the muzzle, above the eyes (tan points) and on the undersides of the dog on otherwise dark coat. Saddle tan resembles black and tan colour but the lighter areas are expanded leaving usually only the back to have dark patch. Saddled tan dogs are usually born black-and-tan and the black recedes as the dog grows.
Additional information
In order for the saddle tan pattern or tan points to be expressed, the dog needs to have at least one copy of the E or Em allele at the E-locus, two copies of the ky allele at the K-locus and two copies of the at allele or at/a at the A-locus.
References
Pubmed ID: 23519866
Omia ID: 1806
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