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The Dominant White coat colour pattern in horses can be caused by any in a wide array of related mutations.
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Specifications
| Breeds | American Quarter Horse, Gypsy Vanner, Oldenburg, American Paint Horse, Appaloosa, German Riding Pony, Noriker, Old-Tori, Thoroughbred, Warmblood, Welsh Pony |
|---|---|
| Gene | |
| Organ | |
| specimen | Hair, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
General information
The Dominant White coat colour pattern in horses can be caused by any in a wide array of related mutations. The resulting pattern can vary anywhere between white markings on the face and legs, up to a completely white coat. Depending on both breed and pattern, variants of the Dominant White phenotype may be referred to as Splashed White, White Spotting, Tobiano or Sabino, among others.
The specific variant analysed in this test, known as Dominant White 20 (W20), is caused by a dominant mutation to the gene KIT. It has been observed in a wide variety of horse breeds.
Clinical features
Dominant White patterns are variable, ranging from minimal Sabino-like spotting to all-white horses. The eye colour of Dominant White horses is brown. One or two copies of the W20 allele have a subtle effect on the amount of white expressed. It appears to increase the expression of white in combination with other white pattern genes.
Additional information
Coat colour is an intricate trait that involves a combination of multiple different genes. Testing for a range of different loci will give the most complete prediction of a horse's coat colour genetics.
Dominant White can be caused by a wide range of mutations. A white-patterned horse that tests as unaffected for a particular mutation will almost certainly be affected by a different one.
References
Pubmed ID: 23659293
Omia ID: 209