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P592

White patterning in horses is known as Dominant White or White.

10 working days

Specifications

Breeds

, , , , , , , , , ,

Gene

Organ

specimen

Hair, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Also known as

Year Published

General information

White patterning in horses is known as Dominant White or White. There are about 20 different mutations identified that are associated with white patterns, all mutations are found in the KIT gene. Except for W20, most of the known Dominant White mutations arose recently and are restricted to specific lines within breeds. The Coat Colour Dominant White 3 test, tests for the mutation known as W20 in the KIT gene. This test detects two variants (alleles). The allele W20 is dominant.

Clinical features

Dominant White patterns are variable, ranging from minimal Sabino-like spotting to all-white horses. The eye colour of Dominant White horses is brown. One or two copies of the W20 allele have a subtle effect on the amount of white expressed. It appears to increase the expression of white in combination with other white pattern genes. The allele N is recessive and does not have an effect on the basic colour.

Additional information

References

Pubmed ID: 23659293

Omia ID: 209

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