Knowledge Base

Copper toxicosis in Labrador Retrievers

Copper toxicosis in Labrador Retrievers Copper toxicosis, also known as copper accumulation or Wilson’s disease, is a common condition in Labrador Retrievers. This disorder results from excessive copper storage in the liver, leading to chronic liver inflammation (Copper Associated Hepatitis, CAH) and a range of serious health issues. What is...

HNPK (Hereditary Nasal Parakeratosis) in the Labrador Retriever

Hereditary Nasal Parakeratosis (HNPK) Hereditary Nasal Parakeratosis (HNPK) is a genetic condition primarily affecting Labrador Retrievers, causing painful cracks and crusts on the nose, often referred to as "crusty nose." DNA testing can help prevent HNPK by identifying carriers before breeding. What is HNPK? HNPK is a genetic disorder that...

Early Adult Onset Deafness (EAOD) in Border Collies

Early Adult Onset Deafness (EAOD) in Border Collies EAOD is a genetic condition affecting the hearing of Border Collies. DNA testing is possible for several risk factors associated with the condition, reducing the risk of passing the condition to future generations. What is Early Adult Onset Deafness (EAOD)? Many dogs...

Degenerative Myelopathy Exon 2 (SOD1A)

Degenerative Myelopathy Exon 2 (SOD1A) Degenerative Myelopathy (DM) is a hereditary condition found in various dog breeds. DM causes degeneration of the spinal cord, leading to a decrease in strength and coordination of the hind legs. The mutation for DM is present in nearly all dog breeds, but in many...

Exercise Induced Collapse (EIC)

Exercise Induced Collapse (EIC) Exercise Induced Collapse, or EIC for short, is a hereditary condition in which the dog weakens or collapses during moments of intense exertion. Symptoms Dogs that suffer from EIC appear completely normal during calm moments, just like any other dog. There is nothing noticeable about them....

Macular Corneal Dystrophy (MCD) in Labrador Retrievers

Macular Corneal Dystrophy (MCD) Many different types of hereditary eye conditions have been described in the Labrador Retriever. During the ECVO eye examination, the dog’s eyes are checked for the presence of a large number of these inherited eye disorders, one of which is Macular Corneal Dystrophy (MCD). In this...

Stargardt Disease in Labrador Retrievers

Stargardt Disease Stargardt Disease (STGD, also known as Stargardt’s Disease) is a hereditary eye condition in Labrador Retrievers and related breeds that causes degeneration (deterioration) of the retina. As a result, the dog gradually loses more and more vision, which can eventually lead to near-total blindness. Symptoms Dogs with Stargardt...

Laryngeal Paralysis and Polyneuropathy, CNTNAP1-related

Laryngeal Paralysis and Polyneuropathy, CNTNAP1-related One of the hereditary conditions that can occur within Labrador Retrievers, Saint Bernards, Great Pyrenees and Leonbergers is Laryngeal Paralysis and Polyneuropathy (LPPN). This is a medical term referring to paralysis of the vocal cords and nerve dysfunction. In practice, this means that dogs suffering...