In the Basenji a potentially severe kidney disorder known as Fanconi Syndrome (FS) occurs. This kidney disorder is caused by a recessive mutation to the gene FAN1.

Symptoms for affected dogs can vary in severity, from a total lack of apparent symptoms to major kidney-related defects. Severely affected dogs present with thirst, excessive urine production, glucosuria, dehydration and weight loss, which can progress to kidney failure. Age of onset can be anywhere between young adulthood to nine years old.

Fanconi Syndrome in the Basenji can be tested with test number H863 or as part of the CombiBreed package Basenji with test number H524.