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K407

The coat pattern known as “Ticking” is one of the variations on a tabby coat in cats, where the typical stripes are blended into a more sandy, even colour.

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Specifications

Breeds

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Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Also known as

Year Published

General information

The coat pattern known as “Ticking” is one of the variations on a tabby coat in cats, where the typical stripes are blended into a more sandy, even colour. A ticked coat can be present due to one of the two known dominant mutations in the Dickkopf WNT Signaling Pathway Inhibitor 4 (DKK4) gene, which regulates hair follicle development and pigmentation. Both mutations lead to the distinctive characteristics of the coat.

The mutation tested for here is known as Ti^CK and is found in Abyssinian, Somali, Burmese, Maine Coon, Siamese, Exotic Longhair and Oriental Short- and longhair breeds. A second mutation (Ti^A) seem to be observed in the Abyssinian and Somali breeds

Clinical features

Ticked describes a coat pattern in which a single hair banding occurs without the coat itself being patterned. Meaning that ticked cats have a more evenly-blended coat pattern than other tabby cats, with a colour distribution often described as “sand-like” or “salt-and-pepper”. In some cases, faint striping (ghost stripes) may still be visible on the lower legs, face and tail. As with all forms of tabby, a ticked coat is only possible if the cat is not affected by the non-agouti mutation (not a/a) and the tabby locus can only be expressed in cats which don’t have mutations on the ticked locus.

Additional information

Coat colour is an intricate trait that involves a combination of multiple different genes. Testing for a range of different loci will give the most complete prediction of a cat’s coat colour genetics.

References

Pubmed ID: 33780570

Omia ID: 1484-9685

How does it work?

1. Select your product(s)

Select your single test, a CombiBreed Package or create your own Bundle.

2. Collect DNA sample

Collect DNA material as indicated with our products and send it to our laboratory.

3. Results

We handle your DNA sample with care and provide you with the results.