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Factor XI (FXI) Deficiency is a disorder that affects blood clotting, which can lead to abnormal, excessive bleeding.
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Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
General information
Factor XI (FXI) Deficiency is a disorder that affects blood clotting, which can lead to abnormal, excessive bleeding. The disease is caused by a recessive mutation to the gene F11, and is found in the Maine Coon.
Clinical features
Signs of Factor XI Deficiency can include easy bruising, bleeding from the gums, hematomas, and excessive bleeding after injury or surgery.
The severity of the disorder's symptoms can be highly variable., and some affected cats may not show any symptoms at all. As such, the mutation should be seen as causing a risk of abnormal bleeding, rather than a guarantee.
Additional information
References
Pubmed ID: 35627175
Omia ID: 363