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Hoof wall separation disease (HWSD) is a genetic defect in horses that causes the hoof wall to crack, chip, and break easily, while the coronary band appears normal.
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Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Hair, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
General information
Hoof wall separation disease (HWSD) is a genetic defect in horses that causes the hoof wall to crack, chip, and break easily, while the coronary band appears normal. Symptoms typically begin in young horses, and in severe cases, the horse may bear weight entirely on the sole of the foot. This abnormal weight-bearing can result in severe pain and lameness. The defect is caused by an autosomal recessive mutation in the serpin peptidase inhibitor, clade B (ovalbumin), member 11 gene (SERPINB11).
HWSD appears to occur in the Connemara Pony, Gypsy Vanner, Tinker and Irish Cob.
Clinical features
Hoof wall separation disease (HWSD) manifests clinically as separation of the dorsal hoof wall along the weight-bearing surface of the hoof during the first year of life.
Additional information
References
Pubmed ID: 25875171
Omia ID: 1897