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Von Willebrand Disease (vWD) is a group of bleeding disorders caused by deficiency in the von Willebrand factor (vWF), which results in poorly functioning blood platelets and can lead to uncontrolled bleeding.

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Specifications

Breeds

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Also known as

Year Published

General information

Von Willebrand Disease (vWD) is a group of bleeding disorders caused by deficiency in the von Willebrand factor (vWF), which results in poorly functioning blood platelets and can lead to uncontrolled bleeding. Type III vWD is the most severe form of the disease, and is caused by a recessive mutation to the gene VWF. This variant of Type III vWD is found in the Scottish Terrier. Related variants are also found in the Shetland Sheepdog and Dutch Kooiker.

Clinical features

Von Willebrand Disease causes disorders of blood clotting which can lead to symptoms such as easy bruising or bleeding. These dogs are often at risk for excessive bleeding during veterinary procedures.

Additional information

References

Pubmed ID: 10668811

Omia ID: 1058

How does it work?

1. Select your product(s)

Select your single test, a CombiBreed Package or create your own Bundle.

2. Collect DNA sample

Collect DNA material as indicated with our products and send it to our laboratory.

3. Results

We handle your DNA sample with care and provide you with the results.

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