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P507

Thrombasthenia also known as Glanzmann's Thrombasthenia (GT) is a rare bleeding disorder characterised by defective platelets.

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Specifications

Breeds

,

Gene

Organ

specimen

Hair, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Year Published

General information

Thrombasthenia also known as Glanzmann’s Thrombasthenia (GT) is a rare bleeding disorder characterised by defective platelets. Normally, platelets stick together to stop the flow of blood during injury until clotting and tissue repair occurs. Dogs with GT have normal platelet counts but have an abnormal platelet aggregation and blood clotting which can result in life-threatening bleeding.

Clinical features

Clinical signs usually are characterised by cutaneous and mucosal bleeding, and may include purpura, epistaxis, gastroin-testinal hemorrhage, and gingival bleeding.

Additional information

References

Pubmed ID: 17338169

Omia ID: 1000

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