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H769

Generalized progressive retinal atrophy (gPRA) is an inherited disease that is characterised by slowly progressive blindness over a period of time.

10 working days

Specifications

Breeds

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Also known as

Year Published

General information

Generalized progressive retinal atrophy (gPRA) is an inherited disease that is characterised by slowly progressive blindness over a period of time. gPRA leads to degeneration of retinal photoreceptor cells in dogs but also in other pets. gPRA shows strong similarities with retinitis pigmentosa (RP) in humans.

Clinical features

gPRA is characterised by poor dark vision, visual field defects which can progress to blindness over a period of time.

Additional information

References

Pubmed ID: 11124530

Omia ID: 1669

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