€57,48 €47,50 excl. VAT
Muscular dystrophy-dystroglycanopathy is a severe muscle disorder that causes weakness, stunted growth and often death.
10 working days
€5,95 shipping and administration per order (incl. VAT)
Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Year Published |
General information
Muscular dystrophy-dystroglycanopathy is a severe muscle disorder that causes weakness, stunted growth and often death. This variant, found in the Labrador Retriever, is caused by a recessive mutation to the gene LARGE1.
Clinical features
Affected puppies present with difficulty suckling, general weakness, poor weight gain (often weighing half as much as healthy littermates) and a bow-legged stance. The puppies may die within the first weeks of life, or are otherwise typically euthanized on humane grounds due to poor quality of life.
Additional information
References
Pubmed ID: 34654610
Omia ID: 2460
Related products
-
- Labrador Retriever
- LOC489707
- Sensory organs
-
- Parson Russell Terrier, Jack Russell Terrier
- CAPN1
- Nervous system
-
- Dachshund, Parson Russell Terrier, Smooth Fox Terrier, Jack Russell Terrier
- KCNJ10
- Nervous system
-
- English Cocker Spaniel, English Springer Spaniel, French Spaniel, German Shorthaired Pointer, English Pointer
- GDNF
- Nervous system
