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Muscular dystrophy-dystroglycanopathy is a severe muscle disorder that causes weakness, stunted growth and often death.
10 working days
Swab, Blood EDTA, Blood Heparin, Semen, Tissue
|Mode of Inheritance|
Muscular dystrophy-dystroglycanopathy is a severe muscle disorder that causes weakness, stunted growth and often death. This variant, found in the Labrador Retriever, is caused by a recessive mutation to the gene LARGE1.
Affected puppies present with difficulty suckling, general weakness, poor weight gain (often weighing half as much as healthy littermates) and a bow-legged stance. The puppies may die within the first weeks of life, and euthanasia is otherwise usually necessary.
Pubmed ID: 34654610
Omia ID: 2460