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K308

The glitter coat in cats is a structural variation of the hair shaft rather than a coat colour trait.

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Specifications

Breeds

, ,

Gene

Chromosome

D2

Mutation

a 585-bp cat-specific Endogenous Retroviral Long Terminal Repeat element insertion

Organ

Specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Autosomal Recessive

Also known as

Glitter

General information

The glitter coat in cats is a structural variation of the hair shaft rather than a coat colour trait. The trait is caused by a mutation in the Fibroblast growth factor receptor (Fgfr2) gene. The Fgfr2 gene plays a role in embryonic development and organ formation. This mutation causes a moderate reduction in Fgfr2 activity, leading to alterations in hair morphology that produce the characteristic glitter effect. The trait is inherited in an autosomal recessive manner and has been identified in Bengal, Egyptian Mau and Toyger.

Clinical features

Cats with this variant exhibit a distinctive sparkling or iridescent sheen across the coat, often described as gold, pearl-like, or crystal-like. The effect can range from subtle shimmer to a pronounced glittering appearance. The coat is typically softer, finer, and silkier compared to cats without the variant. These features result from structural differences within the hair shaft that alter how light is reflected. Expression of the trait can vary between individuals, and it does not impact health or overall quality of life.

Additional information

References

Pubmed ID: 38531359

Year published: 2024

Omia ID: 1313

Omia variant ID:

How does it work?

1. Select your product(s)

Select your single test, a CombiBreed Package or create your own Bundle.

2. Collect DNA sample

Collect DNA material as indicated with our products and send it to our laboratory.

3. Results

We handle your DNA sample with care and provide you with the results.