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H807

Cardiomyopathy with juvenile mortality is a severe heart disorder in the Belgian Shepherd, causing the sudden death of affected puppies.

10 working days

Specifications

Breeds

Gene

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue
Mode of Inheritance

Chromosome

Year Published

General information

Cardiomyopathy with juvenile mortality is a severe heart disorder in the Belgian Shepherd, causing the sudden death of affected puppies. It is caused by a recessive mutation to the gene YARS2.

Clinical features

Affected puppies present at about 8 weeks of age with vomiting, shortness of breath, and sometimes spontaneous bouts of tremors and twitching. Sudden death by heart failure is highly likely.

Additional information

References

Pubmed ID: 32183361

Omia ID: 2256

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