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Cardiomyopathy with juvenile mortality is a severe heart disorder in the Belgian Shepherd, causing the sudden death of affected puppies.
10 working days
Specifications
Breeds | |
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Gene | |
specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
Mode of Inheritance | |
Chromosome | |
Year Published |
General information
Cardiomyopathy with juvenile mortality is a severe heart disorder in the Belgian Shepherd, causing the sudden death of affected puppies. It is caused by a recessive mutation to the gene YARS2.
Clinical features
Affected puppies present at about 8 weeks of age with vomiting, shortness of breath, and sometimes spontaneous bouts of tremors and twitching. Sudden death by heart failure is highly likely.
Additional information
References
Pubmed ID: 32183361
Omia ID: 2256