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Primary lens luxation (PLL) is a defective development or maintance of the zonular fibers, or both.
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Specifications
| Breeds | Chinese Crested, Patterdale Terrier, Sealyham Terrier, Volpino Italiano, German Hunting Terrier, Jack Russell Terrier, Lancashire Heeler, Miniature Bull Terrier, Parson Russell Terrier, Rat Terrier, Tenterfield Terrier, Tibetan Terrier, Toy Fox Terrier, Welsh Terrier, Yorkshire Terrier |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
General information
Primary lens luxation (PLL) is a defective development or maintance of the zonular fibers, or both. The cause of PLL is a mutation in a splice donor recognition site in the ADAMTS17 gene. The disease can be caused due to a trauma or a variety of conditions that effect the ocular anatomy.
Clinical features
PLL can be seen at the moment one of the lenses is displaced from the patellar fossa. Thereby, displacement of the lens in the second eye often follows weeks or months later. Abnormalities of the zonular fibers are evident at 20 months of age.
Additional information
References
Pubmed ID: 20375329
Omia ID: 588
Year published:
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