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Cone-rod dystrophy (CRD) affects the photoreceptor cells in the eye involved in both night and day vision.
10 working days
Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
General information
Cone-rod dystrophy (CRD) affects the photoreceptor cells in the eye involved in both night and day vision. The cells of the retina involved in low light vision, known as rods, are affected first, resulting in night blindness. Subsequently, the bright light photoreceptors known as cones, which are important for colour vision, are also affected, resulting in daytime visual deficit.
Clinical features
Cone-r0d dystrophy affected dogs show a great variation both in age of onset and in clinical appearance of retinal changes upon fundoscopy. The majority of affected puppies (5–10 weeks) show pin-point sized pupils upon examination with focal light. Generalized bilateral retinal atrophy is the end stage of the disease. Electroretinography is found to be the most reliable diagnostic procedure to clinically diagnose CRD.
Additional information
References
Pubmed ID: 18687878
Omia ID: 1455
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