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H495

Polyneuropathy is a neurological disorder characterized by damage to the peripheral nerves.

10 working days

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Specifications

Breeds

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Also known as

Year Published

General information

Polyneuropathy is a neurological disorder characterized by damage to the peripheral nerves. The variant of the disease analysed in this test is found in the Alaskan Malamute, and is known as Alaskan Malamute Polyneuropathy (AMPN). It is caused by a recessive mutation to the gene NDRG1. A related variant, GHPN, is found in the Greyhound.

Clinical features

Clinical features include weakness, numbness, and pain of the feet progressing to the legs and other body parts. The disease can be acute or chronic.

Additional information

References

Pubmed ID: 23393557

Omia ID: 2120

How does it work?

1. Select your product(s)

Select your single test, a CombiBreed Package or create your own Bundle.

2. Collect DNA sample

Collect DNA material as indicated with our products and send it to our laboratory.

3. Results

We handle your DNA sample with care and provide you with the results.

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