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Polyneuropathy is a neurological disorder characterized by damage to the peripheral nerves.
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Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
General information
Polyneuropathy is a neurological disorder characterized by damage to the peripheral nerves. The variant of the disease analysed in this test is found in the Greyhound, and is known as Greyhound Polyneuropathy (GHPN). It is caused by a recessive mutation to the gene NDRG1. A related variant, AMPN, is found in the Alaskan Malamute.
Clinical features
Clinical features include weakness, numbness, and pain of the feet progressing to the legs and other body parts. The disease can be acute or chronic.
Additional information
References
Pubmed ID: 20582309
Omia ID: 2120