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Polydactyly, also known as Preaxial Polydactyly (PPD) is a developmental abnormality in dogs that causes the growth of extra toes on the hind legs.
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Specifications
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Year Published |
General information
Polydactyly, also known as Preaxial Polydactyly (PPD) is a developmental abnormality in dogs that causes the growth of extra toes on the hind legs. Specifically, polydactyly restores the first toe that was lost over the course of the evolution of the wolf, giving affected dogs a fifth toe known as a “dewclaw”. It can be caused by a dominant mutation to the gene LMBR1.
Clinical features
Affected dogs develop an extra toe, or dewclaw, on their hind legs.
Additional information
References
Pubmed ID: 18689889
Omia ID: 810