
€57,48 €47,50 excl. VAT
Focal Non-Epidermolytic Palmoplantar Keratoderma (FNEPPK1) is a skin disorder found in the Dogue de Bordeaux, causing severe and painful thickening and cracking of the paw pads.
10 working days
Specifications
Breeds | |
---|---|
Gene | |
Organ | |
specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
Mode of Inheritance | |
Chromosome | |
Also known as | |
Year Published |
General information
Focal Non-Epidermolytic Palmoplantar Keratoderma (FNEPPK1) is a skin disorder found in the Dogue de Bordeaux, causing severe and painful thickening and cracking of the paw pads. It is caused by a recessive mutation to the gene KRT16.
Clinical features
Onset of FNEPPK can occur anywhere between 10 weeks and 1 year of age. The main symptom is a painful thickening of the paw pads, as well as the formation of cracks and/or lumpy keratinous growths. The cracks pose a risk of infection, which can in turn cause lameness.
Additional information
References
Pubmed ID: 25521457
Omia ID: 2088