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H307

Canine Multifocal Retinopathy (CMR) is an eye disorder characterised by multiple areas of retinal degenerationm, potentially causing a loss of central vision.

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Specifications

Breeds

,

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Also known as

Year Published

General information

Canine Multifocal Retinopathy (CMR) is an eye disorder characterised by multiple areas of retinal degenerationm, potentially causing a loss of central vision. This variant of the disorder, CMR3, occurs specifically in the Lapponian Herder, and is caused by a recessive mutation to the gene BEST1.

Clinical features

On veterinary examination, clinical signs of CMR include multiple tan-pink subretinal patches ("blisters") in both the tapetal and the non-tapetal fundus along with focal areas of tapetal hyper-reflectivity. The disorder does not typically lead to blindness.

Additional information

References

Pubmed ID: 21197113

Omia ID: 1554

How does it work?

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2. Collect DNA sample

Collect DNA material as indicated with our products and send it to our laboratory.

3. Results

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